Science-Backed · Third-Party Tested · Made in USA
Feel Calm Again.
Clinically studied KSM-66® ashwagandha for stress, sleep, and mental clarity.
Third-Party Tested
GMP Certified
Non-GMO
FDA-Audited Facility
Award-Winning
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- ✓ 27.9% cortisol reduction¹
- ✓ Sleep efficiency improved to 83.5%²
- ✓ 90-day money-back guarantee
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Why KSM-66®?
Not all ashwagandha is created equal. Here’s what sets KSM-66® apart.
| Feature | Generic Ashwagandha | Optibio KSM-66® |
|---|---|---|
| Extract Type | ✗ Varies (often leaf-only) | ✓ Full-spectrum root extract |
| Withanolide Content | ✗ 1–2% (unstandardized) | ✓ 5% withanolides (standardized) |
| Clinical Studies | ✗ Few or none | ✓ 24+ peer-reviewed trials |
| Quality Testing | ✗ Unknown or self-tested | ✓ 3rd-party verified (COA available) |
| Clinical Dosage | ✗ Often underdosed | ✓ 600mg full clinical dose |
| Extraction Method | ✗ Chemical solvents common | ✓ Green chemistry (milk-based) |
Extract Type
✗ Generic
Varies (often leaf-only)
✓ Optibio
Full-spectrum root extract
Withanolide Content
✗ Generic
1-2% (unstandardized)
✓ Optibio
5% withanolides (standardized)
Clinical Studies
✗ Generic
Few or none
✓ Optibio
24+ peer-reviewed trials
Quality Testing
✗ Generic
Unknown or self-tested
✓ Optibio
3rd-party verified (COA available)
Clinical Dosage
✗ Generic
Often underdosed
✓ Optibio
600mg full clinical dose
Extraction Method
✗ Generic
Chemical solvents common
✓ Optibio
Green chemistry (milk-based)
Clinically Studied Results
Real outcomes from peer-reviewed, placebo-controlled clinical trials.
¹ Chandrasekhar, K., Kapoor, J., & Anishetty, S. (2012). A prospective, randomized double-blind, placebo-controlled study. Indian J Psychol Med. PubMed 23439798
² Langade, D., Kanchi, S., Salve, J., et al. (2019). Efficacy and safety of Ashwagandha root extract on sleep quality. Cureus. PubMed 31728244
³ Choudhary, B., Shetty, A., & Langade, D.G. (2015). Efficacy of Ashwagandha on endurance capacity. Ayu. PubMed 26730141
What to Expect
Ashwagandha works with your body over time. Here’s a realistic timeline.
1
Week 1–2
Initial Adaptation
Your body begins adapting. You may notice subtle improvements in stress response and a growing sense of calm.
2
Week 3–4
Building Benefits
Most people notice meaningful improvements in sleep quality, sustained energy, and reduced reactivity to daily stressors.
3
Week 5–8
Full Benefits
Cumulative benefits compound: deeper resilience, clearer thinking, better recovery, and consistent well-being.
Results vary. Most customers notice changes within 2–4 weeks of consistent daily use.
Is Optibio Right for You?
✓ Perfect For
- Stressed professionals seeking calm without sedation
- Poor sleepers who want to wake up actually feeling rested
- Active individuals looking for natural endurance support
- Anyone experiencing mental fog or burnout
✗ Not Right For
- Anyone expecting overnight results
- Pregnant or nursing women (consult your doctor)
- Those taking sedatives or thyroid medication (consult your doctor)
- Anyone under 18 years of age
How KSM-66® Works
A clinically studied adaptogen that works with your body’s natural stress response system.
1
Cortisol Regulation
KSM-66® modulates the HPA axis — your body’s central stress command system — to help reduce excess cortisol production.
2
Adaptogenic Response
As an adaptogen, it helps your body build resilience to stressors over time, rather than masking symptoms.
3
Cumulative Benefits
With consistent daily use, benefits compound: better sleep, clearer thinking, calmer days, and improved recovery.
Quality You Can Trust
Every bottle meets the highest standards for purity, potency, and safety.
🏟
GMP Certified
🔬
3rd-Party Tested
🌿
Non-GMO
🌱
Organic KSM-66®
🇺🇸
Made in USA
Manufactured by Optimal Biology Supplements — USA
Every batch tested for purity, potency, and contaminants by independent laboratories.
Certified Quality You Can Trust
🇺🇸
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FDA-Audited Facility
cGMP Certified
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Made in New York
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Frequently Asked Questions
How long until I feel results?
Most customers notice subtle improvements within 1–2 weeks, with more significant benefits emerging at 3–4 weeks of consistent daily use. Full adaptogenic benefits typically develop over 6–8 weeks. Consistency is key — take it daily for best results.
What’s the difference between KSM-66® and regular ashwagandha?
KSM-66® is a patented, full-spectrum root extract standardized to 5% withanolides. Unlike generic ashwagandha (which often uses leaf or a mix), KSM-66® is backed by 24+ peer-reviewed clinical trials and uses a unique milk-based extraction process that preserves the natural balance of active compounds.
Are there any side effects?
KSM-66® ashwagandha is generally well-tolerated in clinical studies. Mild, temporary digestive discomfort has been reported in some cases. If you are taking medications, especially for thyroid conditions, blood pressure, or blood sugar, please consult your healthcare provider before starting any new supplement.
Can I take this with other supplements?
Yes, ashwagandha is generally compatible with most supplements. However, if you are taking prescription medications or other adaptogenic herbs, we recommend consulting your doctor to ensure there are no interactions.
What if it doesn’t work for me?
We offer a 90-day money-back guarantee. If you’re not satisfied with your results after giving it a fair trial (we recommend at least 30 days of consistent use), contact us for a full refund. No questions asked.
How do I take it?
Take 2 capsules daily, preferably with food. You can take both capsules together or split them (one in the morning, one in the evening). For sleep support, some customers prefer taking their dose in the evening.
Is this FDA approved?
Dietary supplements are not evaluated or approved by the FDA in the same way prescription drugs are. However, our product is manufactured in an FDA-registered, GMP-certified facility in the United States, and every batch is third-party tested for purity, potency, and contaminants.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Ready to Feel Calm Again?
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