We don't make claims. We cite trials.
We don't describe how a supplement feels. We point to peer reviewed, placebo controlled human trials of KSM-66® and let you read them. Every number here links to its PubMed source.
Serum cortisol reduction over 60 days in adults with chronic stress, versus placebo. Randomized, double blind.
PubMed 23439798 →Cortisol fell 27.9% over 60 days.
The trial behind the headline number.
- Participants
- 64 adults
- Population
- Chronic stress
- Daily dose
- 600 mg KSM-66®
- Duration
- 60 days
- Design
- RCT · double blind
- Journal
- Indian J Psychol Med
Three more results we keep coming back to.
Significant reduction in perceived stress.
KSM-66® at 600 mg/day significantly improved Perceived Stress Scale scores over 8 weeks in a randomized, double blind, placebo controlled trial.
PubMed 32021735 →Faster onset, deeper sleep.
10 weeks, n=80. Onset latency fell 39%; total sleep time rose 23%.
PubMed 31728244 →VO2max in elite cyclists.
Aerobic capacity rose 13% after 8 weeks. Placebo group: +1.8%.
PubMed 26730141 →50+ clinical studies. Key trials in chronological order.
| 2012 | Chandrasekhar et al. | Indian J Psychol Med | Safety and efficacy of a high concentration full spectrum extract on chronic stress. | PMID → |
| 2015 | Choudhary et al. | AYU | Effect on cardiorespiratory endurance in elite cyclists. | PMID → |
| 2015 | Wankhede et al. | J Int Soc Sports Nutr | Effect on muscle mass and strength in healthy young men. | PMID → |
| 2017 | Pingali et al. | Pharmacognosy Res | Cognitive and memory enhancement effects. | PMID → |
| 2019 | Langade et al. | Cureus | Efficacy and safety in insomnia: a prospective study. | PMID → |
| 2019 | Salve et al. | Cureus | Adaptogenic and anxiolytic effect in healthy adults. | PMID → |
| 2019 | Lopresti et al. | Medicine | Investigation into stress relieving and pharmacological actions. | PMID → |
| 2020 | Kelgane et al. | Cureus | Anti anxiety effect in the elderly: 8 week randomized trial. | PMID → |
| 2021 | Gopukumar et al. | Evid Based Compl Alt Med | Efficacy and safety on stress and improvement in cognition. | PMID → |
+ 15 additional trials available on request · updated quarterly.
The research, in plain language.

How long does ashwagandha take to work?
A straight line answer, drawn from the actual trial timelines. What to expect at week one, four, and eight.

Cortisol, cortisol, cortisol.
What the stress hormone actually does, and what 27.9% really means.
Read →
KSM-66® vs generic ashwagandha.
Why the extract spec on the label matters more than the milligrams beside it.
Read →
The +13% VO2max study, explained.
What a cycling trial tells us about ashwagandha and endurance.
Read →The trial dose, dosed to the trial.
Review the product details, serving size, and guarantee, or verify batch testing before checkout.