Optibio KSM-66® Ashwagandha 600mg Capsules

KSM-66® ashwagandha is most extensively studied for stress and cortisol regulation, sleep quality, and physical endurance. In peer reviewed clinical trials at 600mg/day, the same dose Optibio uses, KSM-66® has been shown to reduce serum cortisol by 27.9% (Chandrasekhar et al., 2012), significantly improve Perceived Stress Scale scores (Salve et al., 2019), significantly improve sleep quality (Langade et al., 2019), and increase VO2max by 13.6% over 12 weeks in athletic adults (Choudhary et al., 2015). It's also been studied for cognitive performance, including memory and focus. Because it's an adaptogen, it works gradually rather than as a stimulant. Most people notice meaningful change within 2 to 4 weeks of daily use.

These results reflect clinical studies of the KSM-66® ashwagandha ingredient used in Optibio, not the finished Optibio product. Individual results may vary.

Read more about ashwagandha's science backed benefits →

Use Optibio consistently as part of a daily wellness routine and follow product directions. Individual experiences vary.

KSM-66® is an ashwagandha root extract standardized to 5% withanolides. KSM-66® has been the subject of numerous published human clinical trials.

Read the full KSM-66® vs generic ashwagandha comparison →

If you are pregnant, nursing, taking medication, have a medical condition, or have questions about whether ashwagandha is right for you, consult your healthcare provider before starting any new supplement.

If you take prescription medications or other supplements, consult your healthcare provider before adding any new supplement to your routine.

We offer a 90 day money back guarantee. If Optibio is not the right fit for your routine, contact us for support under the guarantee.

Yes. Ashwagandha is typically taken daily as part of a consistent routine. KSM-66® is an adaptogen, which means its effects build gradually with regular use. Most clinical studies used daily dosing over 8 to 12 weeks. As with any supplement, consult your healthcare provider if you have questions about long term use.

Either works. It depends on your goals. Some people prefer morning dosing for stress resilience throughout the day, while others take it in the evening to support relaxation and sleep quality. You can also split your two capsules: one in the morning and one in the evening. There is no wrong time.

We recommend taking Optibio with food. While ashwagandha can be taken on an empty stomach, pairing it with a meal supports absorption and is gentler on digestion. A light breakfast or snack is sufficient.

Yes. There is no known adverse interaction between ashwagandha and caffeine. Many people take their morning Optibio capsule alongside coffee. Ashwagandha works through a different pathway (the HPA axis and stress response system) than caffeine, so they complement rather than conflict.

Optibio delivers 600mg of KSM-66® ashwagandha root extract per daily serving (2 capsules), the same dose used in published clinical trials. This is standardized to 5% withanolides, the key bioactive compounds. Do not exceed the recommended dose unless directed by your healthcare provider.

Take 2 capsules daily, preferably with food. You can take both capsules together or split them (one in the morning, one in the evening). For sleep support, some customers prefer taking their dose in the evening.

Dietary supplements are regulated differently from prescription drugs. Optibio keeps quality language limited to approved claims: Manufactured in the USA with globally sourced ingredients, Manufactured in a GMP certified facility, and Third party tested for purity and potency.

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Ashwagandha is sold in capsules, powder, and gummies, but the format affects both dose accuracy and the active compounds you actually receive. KSM-66® ashwagandha capsules like Optibio deliver the exact 600mg clinical dose used in peer reviewed studies, with no added sugar, fillers, or flavor masking. KSM-66® ashwagandha powder can be effective but requires careful measuring and has a strong, bitter taste that's difficult to mask in food. KSM-66® ashwagandha gummies typically contain 1 to 3g of added sugar per serving and are often underdosed at 100 to 250mg per gummy, well below the clinical range. For consistent, accurate dosing without added sugars, capsules are the cleanest delivery format for KSM-66®.